
Paula’s Choice, a leader in clinical skincare and a trusted voice in science-backed beauty, introduces its latest innovation, the CellularYouth Longevity Serum.
This breakthrough formulation is clinically proven to slow down skin’s ageing process at the source and represents the brand’s most clinically studied product to date. Launching on 22 January 2026, the CellularYouth Longevity Serum has been developed over five years of advanced research and marks an exciting turning point in skincare science. Designed to empower consumers to take control of their skin’s health, the serum helps skin look younger for longer by addressing ageing at a cellular level.
At the heart of the formula is NAD+ support. NAD+ (nicotinamide adenine dinucleotide) is a cellular enzyme that fuels the skin’s energy factories. The serum contains specially grown sunflower sprout extract, shown in lab studies to support NAD+ regeneration pathways, ultimately helping to delay and fade visible signs of ageing. The formula also features phyto-exosomes derived from goji berry. These plant-based messengers help support cellular communication for smoother, more resilient skin that is better able to resist future signs of ageing. This lightweight formula features six potent longevity heroes that help prolong skin’s youthful appearance by slowing down the ageing process at the source. Among these is Acetyl Tetrapeptide-2, an AI-optimised peptide that helps improve skin elasticity and hydration to maintain the skin’s structural integrity and resilience as it ages.
Speaking on the innovation, Dr. Timothy Falla, Senior Vice President of Research and Development at Paula’s Choice, says:
“Most longevity solutions focus solely on prevention, ultimately offering limited results. Unlike other treatments, this serum is uniquely formulated to deliver visible and immediate results, while actively preserving the skin’s health for the future. Developed through five years of advanced epigenetic research, this is our most clinically studied formulation to date, targeting 12 visible signs of aging. It goes beyond surface-level fixes, energizing skin at the cellular level and strengthening it from the inside out.”
The lightweight, non-sticky serum absorbs rapidly into the skin to target 12 visible signs of ageing caused by the loss of cellular energy experienced as we age. These include fading discolouration, firming and lifting skin, brightening, smoothing fine lines, reducing the appearance of wrinkles, refining texture, boosting elasticity, strengthening the skin barrier, hydrating, plumping and supporting the skin’s microbiome.
Clinical and consumer studies demonstrate impressive results. One hundred percent of users agreed that skin instantly looks smoother and feels hydrated, while one hundred percent agreed that skin looks more youthful and firmer after three weeks of use. The serum is also clinically proven to improve the appearance of sagging skin, skin smoothness and the appearance of fine lines and wrinkles after eight weeks of use.
The CellularYouth Longevity Serum is priced at £65 for 30ml.


